Postdoctoral Associate - Bhaduri-McIntosh Lab

Classification Title:

Postdoctoral Associate

Job Description:

The Bhaduri-McIntosh lab at the University of Florida seeks a highly motivated Postdoctoral Research Associate to join a team of scientists that are using a cancer-causing virus to dissect DNA replication, DNA damage, and DNA repair.

http://research.pediatrics.med.ufl.edu/researchers/research-faculty/sumita-bhaduri-mcintosh-ph-d/

The Bhaduri lab focuses on discovering fundamental biological pathways by studying interactions between the oncogenic virus Epstein-Barr virus (EBV) and its host, the human B cell. Using EBV, this lab

• Discovered a key role for the cellular transcription factor STAT3 in knocking down the DNA damage response, an intrinsic barrier to cancer. STAT3 is constitutively active in 70% of human cancers and this was the first indication of STAT3’s ability to promote tumorigenesis by interfering with DNA damage response signaling (Koganti, J. Virol 2013; Koganti, PNAS 2014).
• Identified a functional network of proteins involving STAT3 and epigenetic silencing factors that simultaneously repress multiple copies of the viral genome to limit lytic stage-associated pathology to the host while promoting viral persistence and lymphomagenesis (Daigle, J. Virol 2010; Hill, J. Virol 2013; Koganti, J. Virol 2015; Li, J. Virol 2015; Li, Frontiers in Microbiology 2016; Li, PLoS Pathogens 2017). A broad role for STAT3 in restricting herpesvirus replicative phase has since been confirmed in KSHV and HSV1.

The Bhaduri lab provides a highly collaborative environment of graduate students, undergraduate students, post-doctoral fellows and clinical fellows within the group as well as ample opportunity for external collaborations. This is combined with rigorous mentoring to create an individualized development plan to achieve the career goals of each team member.

Advertised Salary:

$47,476-$50,000 commensurate with qualifications and experience

Minimum Requirements:

Ph.D. in Biological Sciences. Research experience in mammalian DNA damage response, DNA repair or DNA replication. Experience in molecular biology and DNA replication and repair assays.

Preferred Qualifications:

Experience in Virology. Proficiency in spoken and written English. At least two publications in English Scientific Journals.

Special Instructions to Applicants:

Please submit curriculum vitae, synopsis of past work, and contact information of 3 references to Dr. Sumita Bhaduri-McIntosh via the online posting.

Final candidate will be required to provide official transcript to the hiring department upon hire. A transcript will not be considered “official” if a designation of “Issued to Student” is visible. Degrees earned from an education institution outside of the United States are required to be evaluated by a professional credentialing service provider approved by National Association of Credential Evaluation Services (NACES), which can be found at http://www.naces.org/.

The University of Florida is an equal opportunity institution dedicated to building a broadly diverse and inclusive faculty and staff. If an accommodation due to a disability is needed to apply for this position, please call 352/392-2477 or the Florida Relay System at 800/955-8771 (TDD). Hiring is contingent upon eligibility to work in the US. Searches are conducted in accordance with Florida's Sunshine Law.

Application must be submitted by 11:55 p.m. (EDT) of the posting end date.

This requisition has been reposted. Previous applicants are still under consideration and need not apply.

Health Assessment Required: Yes